新冠病毒多肽概述

專肽生物致力于為全球科研機(jī)構(gòu)提供快速優(yōu)質(zhì)新冠病毒(SARS-CoV-2)研究相關(guān)多肽。針對熱門靶點(diǎn)，專肽生物專家團(tuán)隊已經(jīng)設(shè)計合成新冠病毒相關(guān)多肽，全方位提供支持。

HCoV-229E Spike Glycoprotein

蛋白種類：Human coronavirus 229E (HCoV-229E) Spike glycoprotein

周期：3周

設(shè)計原則：多肽條數(shù)291條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MFVLLVAYAL LHIAGCQTTN GLNTSYSVCN GCVGYSENVF AVESGGYIPS DFAFNNWFLL TNTSSVVDGV

VRSFQPLLLN CLWSVSGLRF TTGFVYFNGT GRGDCKGFSS DVLSDVIRYN LNFEENLRRG TILFKTSYGV

VVFYCTNNTL VSGDAHIPFG TVLGNFYCFV NTTIGNETTS AFVGALPKTV REFVISRTGH FYINGYRYFT

LGNVEAVNFN VTTAETTDFC TVALASYADV LVNVSQTSIA NIIYCNSVIN RLRCDQLSFD VPDGFYSTSP

IQSVELPVSI VSLPVYHKHT FIVLYVDFKP QSGGGKCFNC YPAGVNITLA NFNETKGPLC VDTSHFTTKY

VAVYANVGRW SASINTGNCP FSFGKVNNFV KFGSVCFSLK DIPGGCAMPI VANWAYSKYY TIGSLYVSWS

DGDGITGVPQ PVEGVSSFMN VTLDKCTKYN IYDVSGVGVI RVSNDTFLNG ITYTSTSGNL LGFKDVTKGT

IYSITPCNPP DQLVVYQQAV VGAMLSENFT SYGFSNVVEL PKFFYASNGT YNCTDAVLTY SSFGVCADGS

IIAVQPRNVS YDSVSAIVTA NLSIPSNWTT SVQVEYLQIT STPIVVDCST YVCNGNVRCV ELLKQYTSAC

KTIEDALRNS ARLESADVSE MLTFDKKAFT LANVSSFGDY NLSSVIPSLP TSGSRVAGRS AIEDILFSKL

VTSGLGTVDA DYKKCTKGLS IADLACAQYY NGIMVLPGVA DAERMAMYTG SLIGGIALGG LTSAVSIPFS

LAIQARLNYV ALQTDVLQEN QKILAASFNK AMTNIVDAFT GVNDAITQTS QALQTVATAL NKIQDVVNQQ

GNSLNHLTSQ LRQNFQAISS SIQAIYDRLD TIQADQQVDR LITGRLAALN VFVSHTLTKY TEVRASRQLA

QQKVNECVKS QSKRYGFCGN GTHIFSIVNA APEGLVFLHT VLLPTQYKDV EAWSGLCVDG TNGYVLRQPN

LALYKEGNYY RITSRIMFEP RIPTMADFVQ IENCNVTFVN ISRSELQTIV PEYIDVNKTL QELSYKLPNY

TVPDLVVEQY NQTILNLTSE ISTLENKSAE LNYTVQKLQT LIDNINSTLV DLKWLNRVET YIKWPWWVWL

CISVVLIFVV SMLLLCCCST GCCGFFSCFA SSIRGCCEST KLPYYDVEKI HIQ

HCoV-OC43 Spike glycoprotein

蛋白種類：Human coronavirus OC43 (HCoV-OC43) Spike glycoprotein

周期：3周

設(shè)計原則：多肽條數(shù)336條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MFLILLISLP TAFAVIGDLK CTSDNINDKD TGPPPISTDT VDVTNGLGTY YVLDRVYLNT TLFLNGYYPT

SGSTYRNMAL KGSVLLSRLW FKPPFLSDFI NGIFAKVKNT KVIKDRVMYS EFPAITIGST FVNTSYSVVV

QPRTINSTQD GDNKLQGLLE VSVCQYNMCE YPQTICHPNL GNHRKELWHL DTGVVSCLYK RNFTYDVNAD

YLYFHFYQEG GTFYAYFTDT GVVTKFLFNV YLGMALSHYY VMPLTCNSKL TLEYWVTPLT SRQYLLAFNQ

DGIIFNAEDC MSDFMSEIKC KTQSIAPPTG VYELNGYTVQ PIADVYRRKP NLPNCNIEAW LNDKSVPSPL

NWERKTFSNC NFNMSSLMSF IQADSFTCNN IDAAKIYGMC FSSITIDKFA IPNGRKVDLQ LGNLGYLQSF

NYRIDTTATS CQLYYNLPAA NVSVSRFNPS TWNKRFGFIE DSVFKPRPAG VLTNHDVVYA QHCFKAPKNF

CPCKLNGSCV GSGPGKNNGI GTCPAGTNYL TCDNLCTPDP ITFTGTYKCP QTKSLVGIGE HCSGLAVKSD

YCGGNSCTCR PQAFLGWSAD SCLQGDKCNI FANFILHDVN SGLTCSTDLQ KANTDIILGV CVNYDLYGIL

GQGIFVEVNA TYYNSWQNLL YDSNGNLYGF RDYIINRTFM IRSCYSGRVS AAFHANSSEP ALLFRNIKCN

YVFNNSLTRQ LQPINYFDSY LGCVVNAYNS TAISVQTCDL TVGSGYCVDY SKNRRSRGAI TTGYRFTNFE

PFTVNSVNDS LEPVGGLYEI QIPSEFTIGN MVEFIQTSSP KVTIDCAAFV CGDYAACKSQ LVEYGSFCDN

INAILTEVNE LLDTTQLQVA NSLMNGVTLS TKLKDGVNFN VDDINFSPVL GCLGSECSKA SSRSAIEDLL

FDKVKLSDVG FVEAYNNCTG GAEIRDLICV QSYKGIKVLP PLLSENQISG YTLAATSASL FPPWTAAAGV

PFYLNVQYRI NGLGVTMDVL SQNQKLIANA FNNALYAIQE GFDATNSALV KIQAVVNANA EALNNLLQQL

SNRFGAISAS LQEILSRLDA LEAEAQIDRL INGRLTALNA YVSQQLSDST LVKFSAAQAM EKVNECVKSQ

SSRINFCGNG NHIISLVQNA PYGLYFIHFS YVPTKYVTAR VSPGLCIAGD RGIAPKSGYF VNVNNTWMYT

GSGYYYPEPI TENNVVVMST CAVNYTKAPY VMLNTSIPNL PDFKEELDQW FKNQTSVAPD LSLDYINVTF

LDLQVEMNRL QEAIKVLNQS YINLKDIGTY EYYVKWPWYV WLLICLAGVA MLVLLFFICC CTGCGTSCFK

KCGGCCDDYT GYQELVIKTS HDD

SARS-CoV-2 ORF3a

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Protein 3a

周期：3周

設(shè)計原則：多肽條數(shù)66條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MDLFMRIFTI GTVTLKQGEI KDATPSDFVR ATATIPIQAS LPFGWLIVGV ALLAVFQSAS KIITLKKRWQ

LALSKGVHFV CNLLLLFVTV YSHLLLVAAG LEAPFLYLYA LVYFLQSINF VRIIMRLWLC WKCRSKNPLL

YDANYFLCWH TNCYDYCIPY NSVTSSIVIT SGDGTTSPIS EHDYQIGGYT EKWESGVKDC VVLHSYFTSD

YYQLYSTQLS TDTGVEHVTF FIYNKIVDEP EEHVQIHTID GSSGVVNPVM EPIYDEPTTT TSVPL

SARS-CoV-2 N

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Nucleoprotein

周期：3周

設(shè)計原則：多肽條數(shù)102條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MSDNGPQNQR NAPRITFGGP SDSTGSNQNG ERSGARSKQR RPQGLPNNTA SWFTALTQHG KEDLKFPRGQ

GVPINTNSSP DDQIGYYRRA TRRIRGGDGK MKDLSPRWYF YYLGTGPEAG LPYGANKDGI IWVATEGALN

TPKDHIGTRN PANNAAIVLQ LPQGTTLPKG FYAEGSRGGS QASSRSSSRS RNSSRNSTPG SSRGTSPARM

AGNGGDAALA LLLLDRLNQL ESKMSGKGQQ QQGQTVTKKS AAEASKKPRQ KRTATKAYNV TQAFGRRGPE

QTQGNFGDQE LIRQGTDYKH WPQIAQFAPS ASAFFGMSRI GMEVTPSGTW LTYTGAIKLD DKDPNFKDQV

ILLNKHIDAY KTFPPTEPKK DKKKKADETQ ALPQRQKKQQ TVTLLPAADL DDFSKQLQQS MSSADSTQA

SARS-CoV-2 ORF6

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Non-structural protein 6

周期：2周

設(shè)計原則：多肽條數(shù)291條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MFHLVDFQVT IAEILLIIMR TFKVSIWNLD YIINLIIKNL SKSLTENKYS QLDEEQPMEI D

SARS-CoV-2 ORF7b

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Non-structural Protein 7b

周期：3周

設(shè)計原則：多肽條數(shù)8條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MIELSLIDFY LCFLAFLLFL VLIMLIIFWF SLELQDHNET CHA

SARS-CoV-2 ORF7a

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Non-structural protein 7A

周期：3周

設(shè)計原則：多肽條數(shù)28條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MKIILFLALI TLATCELYHY QECVRGTTVL LKEPCSSGTY EGNSPFHPLA DNKFALTCFS TQFAFACPDG

VKHVYQLRAR SVSPKLFIRQ EEVQELYSPI FLIVAAIVFI TLCFTLKRKT E

SARS-CoV-2 ORF8

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Non-structural protein 8

周期：2周

設(shè)計原則：多肽條數(shù)28條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MKFLVFLGII TTVAAFHQEC SLQSCTQHQP YVVDDPCPIH FYSKWYIRVG ARKSAPLIEL CVDEAGSKSP

IQYIDIGNYT VSCLPFTINC QEPKLGSLVV RCSFYEDFLE YHDVRVVLDF I

SARS-CoV-2 ORF10

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) ORF10 Protein

周期：2周

設(shè)計原則：多肽條數(shù)7條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MGYINVFAFP FTIYSLLLCR MNSRNYIAQV DVVNFNLT

SARS-CoV-2 ORF9B

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Protein 9b

周期：2周

設(shè)計原則：多肽條數(shù)22條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MDPKISEMHP ALRLVDPQIQ LAVTRMENAV GRDQNNVGPK VYPIILRLGS PLSLNMARKT LNSLEDKAFQ

LTPIAVQMTK LATTEELPDE FVVVTVK

SARS-CoV-2 Spike Glycoprotein)

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Spike glycoprotein

周期：3-4周

設(shè)計原則：多肽條數(shù)315條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MFVFLVLLPL VSSQCVNLTT RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV

SGTNGTKRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF

LGVYYHKNNK SWMESEFRVY SSANNCTFEY VSQPFLMDLE GKQGNFKNLR EFVFKNIDGY FKIYSKHTPI

NLVRDLPQGF SALEPLVDLP IGINITRFQT LLALHRSYLT PGDSSSGWTA GAAAYYVGYL QPRTFLLKYN

ENGTITDAVD CALDPLSETK CTLKSFTVEK GIYQTSNFRV QPTESIVRFP NITNLCPFGE VFNATRFASV

YAWNRKRISN CVADYSVLYN SASFSTFKCY GVSPTKLNDL CFTNVYADSF VIRGDEVRQI APGQTGKIAD

YNYKLPDDFT GCVIAWNSNN LDSKVGGNYN YLYRLFRKSN LKPFERDIST EIYQAGSTPC NGVEGFNCYF

PLQSYGFQPT NGVGYQPYRV VVLSFELLHA PATVCGPKKS TNLVKNKCVN FNFNGLTGTG VLTESNKKFL

PFQQFGRDIA DTTDAVRDPQ TLEILDITPC SFGGVSVITP GTNTSNQVAV LYQDVNCTEV PVAIHADQLT

PTWRVYSTGS NVFQTRAGCL IGAEHVNNSY ECDIPIGAGI CASYQTQTNS PRRARSVASQ SIIAYTMSLG

AENSVAYSNN SIAIPTNFTI SVTTEILPVS MTKTSVDCTM YICGDSTECS NLLLQYGSFC TQLNRALTGI

AVEQDKNTQE VFAQVKQIYK TPPIKDFGGF NFSQILPDPS KPSKRSFIED LLFNKVTLAD AGFIKQYGDC

LGDIAARDLI CAQKFNGLTV LPPLLTDEMI AQYTSALLAG TITSGWTFGA GAALQIPFAM QMAYRFNGIG

VTQNVLYENQ KLIANQFNSA IGKIQDSLSS TASALGKLQD VVNQNAQALN TLVKQLSSNF GAISSVLNDI

LSRLDKVEAE VQIDRLITGR LQSLQTYVTQ QLIRAAEIRA SANLAATKMS ECVLGQSKRV DFCGKGYHLM

SFPQSAPHGV VFLHVTYVPA QEKNFTTAPA ICHDGKAHFP REGVFVSNGT HWFVTQRNFY EPQIITTDNT

FVSGNCDVVI GIVNNTVYDP LQPELDSFKE ELDKYFKNHT SPDVDLGDIS GINASVVNIQ KEIDRLNEVA

KNLNESLIDL QELGKYEQYI KWPWYIWLGF IAGLIAIVMV TIMLCCMTSC CSCLKGCCSC GSCCKFDEDD

SEPVLKGVKL HYT

SARS-CoV-2 E

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Envelope small membrane protein

周期：2周

設(shè)計原則：多肽條數(shù)16條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MYSFVSEETG TLIVNSVLLF LAFVVFLLVT LAILTALRLC AYCCNIVNVS LVKPSFYVYS RVKNLNSSRVPDLLV

SARS-CoV-2 M

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Membrane protein

周期：2周

設(shè)計原則：多肽條數(shù)53條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MADSNGTITV EELKKLLEQW NLVIGFLFLT WICLLQFAYA NRNRFLYIIK LIFLWLLWPV TLACFVLAAVYRINWITGGI AIAMACLVGL MWLSYFIASF RLFARTRSMW SFNPETNILL NVPLHGTILT RPLLESELVIGAVILRGHLR IAGHHLGRCD IKDLPKEITV ATSRTLSYYKLGASQRVAGD SGFAAYSRYR IGNYKLNTDHSSSSDNIALL VQ

SARS-CoV-2 Y14

蛋白種類：SARSr-CoV (Severe Acute Respiratory Syndrome-related coronavirus 2) Uncharacterized protein 14

周期：2周

設(shè)計原則：多肽條數(shù)16條• 多肽長度15AA• 重疊氨基酸數(shù)11AA

序列：MLQSCYNFLK EQHCQKASTQ KGAEAAVKPL LVPHHVVATV QEIQLQAAVG ELLLLEWLAM AVMLLLLCCC

LTD