400-998-5282
專注多肽 服務(wù)科研
腸/脊椎動(dòng)物膠原酶 (MMP-1)、溶基質(zhì)素 (MMP-3)、明膠酶(MMP-2 和 MMP-9)和間斷金屬蛋白酶 (MMP-7) 的有效底物。
編號(hào):163461
CAS號(hào):121282-17-5
單字母:Dnp-PLGLWAr-CONH2
腸/脊椎動(dòng)物膠原酶 (MMP-1)、溶基質(zhì)素 (MMP-3)、明膠酶(MMP-2 和 MMP-9)和間斷金屬蛋白酶 (MMP-7) 的有效底物。
The FRET peptide Dnp-PLGLWAr-amide is an efficient substrate for interstitial/vertebrate collagenase (MMP-1), stromelysin (MMP-3), and especially for the gelatinases (MMP-2 and MMP-9) and the punctuated metalloproteinase (MMP-7).
很多蛋白在細(xì)胞中非常容易被降解,或被標(biāo)記,進(jìn)而被選擇性地破壞。但含有部分D型氨基酸的多肽則顯示了很強(qiáng)的抵抗蛋白酶降解能力。
DOI | 名稱 | |
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10.1074/jbc.M205071200 | Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26 | 下載 |
10.1016/j.ymthe.2003.10.004 | Efficient retroviral vector targeting of carcinoembryonic antigen-positive tumors | 下載 |
10.1016/0014-5793(92)80300-6 | A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases | 下載 |
10.1016/0006-2944(77)90026-6 | Synthetic substrates for vertebrate collagenase | 下載 |
10.1002/anie.201405727 | Multiple stable conformations account for reversible concentration-dependent oligomerization and autoinhibition of a metamorphic metallopeptidase | 下載 |
10.1006/abio.1993.1291 | A high throughput fluorogenic substrate for interstitial collagenase (MMP-1) and gelatinase (MMP-9) | 下載 |
10.1074/jbc.M113.476580 | A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases | 下載 |
10.1002/ijc.2910560415 | Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma | 下載 |